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博士生导师简介

 

冯国忠

专业学科:微生物学

研究方向:农业微生物与应用技术

 

冯国忠,男,博士,研究员,博士生导师。中国水稻研究所水稻生物学国家重点实验室课题组长。2007年获中山大学博士学位, 2009年起在加拿大圭尔夫大学(University of Guelph)进行博士后研究,2013年底进入中国水稻研究所工作,建立生物农药研究组,主要从事病毒复制以及微生物代谢产物的抗病毒研究。迄今在Journal of Virology, J Gen Virol., Virology等国际著名的杂志发表论文多篇。

主要研究方向

  1. 病毒复制的研究:重点研究杆状病毒的复制和水稻病毒的复制,以及微生物代谢产物抑制病毒复制的机理。

  2. 微生物代谢产物的抗病毒研究:微生物代谢产物的筛选,活性代谢产物基因簇的分离及其生物组合合成。

承担的科研项目

  1. 杆状病毒DNA聚合酶入核机理的研究,国家自然科学基金面上项目,2016.01-2019.12, 58万。

  2. “微生物资源与生物农药”创新团队,中国农业科学院创新团队项目,2015.01-2018.12,200万。

  3. 水稻生物农药的研究,中国农业科学院“青年英才计划”项目,2014.10-2019.09,200万。

专家类别

中国农业科学院“青年英才计划”A类入选者,

中国农业科学院“微生物资源与生物农药”创新团队首席科学家

国际合作

  1. 加拿大圭尔夫大学(University of Guelph)的Peter Krell教授和 Baozhong Meng教授。

  2. 加拿大大湖森林中心(Great Lake Forestry Centre)的Basil Arif研究员以及Guoxin Quan研究员。

代表性论文(✻ 为通讯作者)

  1. Chen G, Yan Q, Fang Y, Wu L, Krell PJ, Feng G✻. The N terminus of Autographa californica Multiple Nucleopolyhedrovirus DNA Polymerase is Required for Efficient Viral DNA Replication and Virus and Occlusion Body Production. J Virol. 2018, doi: 10.1128/JVI.00398-18.

  2. Yan Q, Xu Y, Yu Y, Zhu ZW, Feng G✻. Effects of pharmaceuticals on microbial communities and activity of soil enzymes in mesocosm-scale constructed wetlands. Chemosphere. 2018, 18;212:245-253. doi: 10.1016/j.chemosphere.

  3. Wu L, Xiao W, Chen G, Song D, Khaskheli MA, Li P, Zhang S, Feng G✻. Identification of Pseudomonas mosselii BS011 gene clusters required for suppression of Rice Blast Fungus Magnaporthe oryzae. J Biotechnol. 2018 Sep 20;282:1-9. doi: 10.1016/j.jbiotec.2018.04.016.

  4. Yan Q, Min J, Yu Y, Zhu Z, Feng G✻. Microbial community response during the treatment of pharmaceutically active compounds (PhACs) in constructed wetland mesocosms. Chemosphere. 2017. doi: 10.1016/j.chemosphere.2017.08.064.

  5. Chen G, Fang Y, Wu L, Yan Q, Krell P J, Feng G✻. A betabaculovirus DNA polymerase cannot substitute for the DNA polymerase of the alphabaculovirus Autographa californica nucleopolyhedrovirus. Arch Virol. 2017, doi: 10.1007/s00705-017-3468-0

  6. Wu L, Chen G, Feng G✻. Complete genome sequence of Streptomyces griseochromogenes ATCC 14511T, a producer of nucleoside compounds and diverse secondary metabolites. J Biotechnol. 2017, 10;249:16-19

  7. Yan Q, Gao X, Guo JS, Zhu ZW, Feng G✻. Insights into the molecular mechanism of the responses for Cyperus alternifolius to PhACs stress in constructed wetlands. Chemosphere. 2016, 164:278-289.

  8. Chen G, Fang Y, Wu L, Hu Z, Krell P J, Feng G✻. The DNA polymerase of Spodoptera litura nucleopolyhedroviruses: rescue of dnapol-null Autographa californica mutiple nucleopolyhedroviruses and identification of a nuclear localization signal. Journal of General Virology, 2016 . 97(8):1968-80.

  9. Fang Y, Wu L, Chen G, Feng G✻. Complete genome sequence of Pseudomonas azotoformans S4, a potential biocontrol bacterium. J Biotechnol. 2016. 10;227:25-6.

  10. Yan Q, Feng G✻, Gao X, Sun C, Guo JS, Zhu Z. Removal of pharmaceutically active compounds (PhACs) and toxicological response of Cyperus alternifolius exposed to PhACs in microcosm constructed wetlands. J Hazard Mater. 2016. 15;301:566-75

  11. Feng G, Krell P J. Autographa californica Multiple Nucleopolyhedrovirus DNA Polymerase C-terminus is Required for Nuclear Localization and Viral DNA Replication. Journal of Virology, 2014, 88(18):10918-33.

  12. Feng G, Thumbi D, Arif B, Doucet D, Krell P J.. Selection and Characterization of Autographa californica Multiple Nucleopolyhedrovirus (AcMNPV) DNA Polymerase Mutations. Journal of Virology, 86(24):13576-88.

  13. Feng G, Yu Q, Hu C, Wang Y, Chen Q, Yang K, Pang Y. Apoptosis is induced in hemolymph and fat body of Spodoptera exigua larvae upon Spodoptera litura multiple nucleopolyhedrovirus oral inoculation. J Gen Virol., 88(8):2185-93.

  14. Yu Q, Lin T, Feng G, Yang K, Pang Y. Functional analysis of the putative antiapoptotic genes, p49 and iap4, of Spodoptera litura nucleopolyhedrovirus with RNAi. J Gen Virol., 89(8):1873-80.

  15. Wang Y, Wu W, Li Z, Yuan M, Feng G, Yu Q, Yang K, Pang Y. Ac18 is not essential for the propagation of Autographa californica multiple nucleopolyhedrovirus. Virology, 367(1):71-81.

  16. Feng G, Wan S, Pan D. Isolation of antifeeding component from wild rice Oryza puncyata and effect on digestive enzyme of Spodoptera litura (Fabricius) (Lepidoptera: Noctuidae). Acta Entomologica Sinica, 49(4):556-561.

 

通讯地址:浙江省杭州市体育场路359号 中国水稻研究所 310006

或浙江省杭州市富阳区新桥水稻所路28号 中国水稻研究所 311400

电  话:0571-63370220

电子邮箱:fengguozhong @caas.cn

 

欢迎有志于从事生物农药研究的本科生和研究生报考本组!


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内容更新日期:2018-10-01